Web12 Apr 2011 · H Lai, M A Carino, R Sperry, A Horita, Effects of microinjection of 2-chloro-11 (2-dimethylaminoethoxy)-dibenzo[b,f]-thiepine (zotepine), thioridazine and haloperidol into … WebZotepine was absorbed rapidly and almost completely from the gastrointestinal tract in all species after oral dosing. The serum level of the unchanged drug in man was comparatively higher than in animals. The serum half-lives of zotepine after i.v. dosing were approximately 3.2 h in rats, 1.5 h in mice and 3.0 h in dogs.
thiépine - Wiktionary
WebOxepine and Thiepine Systems 1a and 1b Considering firstly the perfluoro-oxepine 1a , vibrational analysis of the planar system (of C 2v symmetry) predicts a single imaginary … Web1 Nov 2024 · The title compound was prepared from dibenzo[c,e]oxepine-5(7H)-one and Lawesson's reagent in refluxing toluene. The structure is comprised of a network of … spies black friday
Pharmacological study of [2-chloro-11-(2-dimethylaminoethoxy) …
Web9 Jul 2015 · A facile synthesis of thiepine sulfones is described. It relies on a sequence of Rh (III)-catalyzed C–H cleavage, 1,5-H shift, and intramolecular allene insertion. As a result of extremely readily accessible starting materials and convenient operation, this protocol should be an appealing strategy in organic synthesis. View via Publisher In organic chemistry, thiepine (or thiepin) is an unsaturated seven-membered heterocyclic compound, with six carbon atoms and one sulfur atom. The parent compound, C6H6S is unstable and is predicted to be antiaromatic. Bulky derivatives have been isolated and shown by X-ray crystallography to have … See more • Thiazepines • 2,3-Dihydrothiepine • 2,7-Dihydrothiepine See more • Thiepins at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Benzothiepins at the U.S. National Library of Medicine Medical Subject Headings See more WebThe synthesis of aryl-fused 1,4-oxathiepines from pyridinium 1, 4-zwitterionic thiolates with ortho-alkynyl aromatic phenols has been achieved in good to excellent yields under mild conditions. The synthesis of aryl-fused 1,4-oxathiepines from pyridinium 1,4-zwitterionic thiolates with ortho-alkynyl aromatic phenols has been achieved in good to excellent … spies among us:modern-day espionage