WebJul 25, 2024 · Increased CD47 expression on the surface of neutrophils was associated with a delay in neutrophil apoptosis and with an impairment in their phagocytic clearance by … WebJun 30, 2024 · To produce EXOs CD47, ADMSCs were transfected with lentiviral vectors. When the cell density was 60%–70% in 100 mm Petri dishes, the medium was …
Abstract LB-208: CD47 blockade with temozolomide can enhance …
WebBarrera L, Montes-Servín E, Hernandez-Martinez J-M, et al. CD47 overexpression is associated with decreased neutrophil apoptosis/phagocytosis and poor prognosis in non-small-cell lung cancer ... Peatman EJ, Reaves TA, Lee WY, Parkos CA. CD47 and TLR-2 cross-talk regulates neutrophil transmigration. J Immunol. 2009;183(9):5957–5963. doi:10 ... WebDec 7, 2024 · The P-gp overexpression and TSP-1/CD47 interaction contributed to the development of this resistance. In fact, inhibition of P-gp function by VPL reduced CD47 … ifleches femme
Frontiers Thrombospondin-1 Receptor CD47 Overexpression …
WebJun 13, 2024 · Wang, Z. H. et al. CD47 overexpression is associated with Epstein–Barr virus infection and poor prognosis in patients with nasopharyngeal carcinoma. Onco Targets … WebDec 1, 2024 · Transgenic CD47 overexpression is an encouraging approach to ameliorating xenograft rejection and alloresponses to pluripotent stem cells, and the efficacy correlates with the level of CD47 expression. However, CD47, upon ligation, also transmits signals leading to cell dysfunction or death, ... WebThe present invention further relates to a pharmaceutical composition comprising a first active agent for use in a method of treating a condition in a subject that would benefit from reducing the signaling or the binding between SIRPa and CD47 in the subject (e.g. cancer), wherein the method of treating comprises reducing expression or enzymatic activity of … ifleches lci